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BTK inhibitor 4b
CAS No. 1646608-10-7
BTK inhibitor 4b( —— )
Catalog No. M12514 CAS No. 1646608-10-7
BTK inhibitor 4b is a potent, highly selective inhibitors of BTK with IC50 of 4.2 and 0.9 nM against activated and unactivated BTK, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1143 | Get Quote |
|
| 50MG | 2322 | Get Quote |
|
| 100MG | 3060 | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameBTK inhibitor 4b
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NoteResearch use only, not for human use.
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Brief DescriptionBTK inhibitor 4b is a potent, highly selective inhibitors of BTK with IC50 of 4.2 and 0.9 nM against activated and unactivated BTK, respectively.
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DescriptionBTK inhibitor 4b is a potent, highly selective inhibitors of BTK with IC50 of 4.2 and 0.9 nM against activated and unactivated BTK, respectively; demonstrates significant efficacy in models in vivo and good ADME and safety profiles.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayTyrosine Kinase
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TargetBTK
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RecptorBTK
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Research Area——
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Indication——
Chemical Information
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CAS Number1646608-10-7
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Formula Weight498.522
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Molecular FormulaC26H23FN8O2
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Purity>98% (HPLC)
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Solubility——
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SMILESCN1C=C(C=N1)NC2=NC(=NC(=N2)N)C3=C(C(=CC=C3)N4C=CC5=CC(=CC(=C5C4=O)F)C6CC6)CO
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Chemical Name2-(3-{4-Amino-6-[(1-methyl-1H-pyrazol-4-yl)amino]-1,3,5-triazin-2-yl}-2-(hydroxymethyl)phenyl)-6-cyclopropyl-8-fluoroisoquinolin-1(2H)-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kawahata W, et al. J Med Chem. 2018 Oct 11;61(19):8917-8933.
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